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Network compensation of cyclic GMP-dependent protein kinase II knockout in the hippocampus by Ca(2+)-permeable AMPA receptors
Gene knockout (KO) does not always result in phenotypic changes, possibly due to mechanisms of functional compensation. We have studied mice lacking cGMP-dependent kinase II (cGKII), which phosphorylates GluA1, a subunit of AMPA receptors (AMPARs), and promotes hippocampal long-term potentiation (LT...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364185/ https://ncbi.nlm.nih.gov/pubmed/25713349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417498112 |
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