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Gain of Nrf2 Function in Non-Small-Cell Lung Cancer Cells Confers Radioresistance
Nuclear factor erythroid-2 related factor 2 (Nrf2), a redox-sensitive transcription factor, regulates the expression of antioxidant enzymes and several anti-apoptotic proteins, which confer cytoprotection against oxidative stress and apoptosis. Constitutive activation of Nrf2 in lung cancer cells pr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3541552/ https://ncbi.nlm.nih.gov/pubmed/20446773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3219 |
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