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Gain of Nrf2 Function in Non-Small-Cell Lung Cancer Cells Confers Radioresistance

Nuclear factor erythroid-2 related factor 2 (Nrf2), a redox-sensitive transcription factor, regulates the expression of antioxidant enzymes and several anti-apoptotic proteins, which confer cytoprotection against oxidative stress and apoptosis. Constitutive activation of Nrf2 in lung cancer cells pr...

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Bibliografske podrobnosti
Main Authors: Singh, Anju, Bodas, Manish, Wakabayashi, Nobunao, Bunz, Fred, Biswal, Shyam
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541552/
https://ncbi.nlm.nih.gov/pubmed/20446773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3219
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