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Death or secretion? The demise of a plausible assumption about CSF-tau in Alzheimer Disease?

Our recent identification of an exosomal route for tau protein secretion(1) marks a key similarity between tau and other aggregation-prone proteins implicated in neurodegenerative disease pathogenesis and is to some extent congruent with the popular idea that tau pathology spreads between neurons vi...

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Autori principali: Hall, Garth F., Saman, Sudad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541332/
https://ncbi.nlm.nih.gov/pubmed/23740221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.21437
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