Doxorubicin-enriched, ALDH(br) mouse breast cancer stem cells are treatable to oncolytic herpes simplex virus type 1

BACKGROUND: The primary objective of this study was to test whether oncolytic herpes simplex virus type 1 (HSV1) could eradicate chemoresistant cancer stem cells (CSCs). METHODS: The fluorescent aldefluor reagent-based technique was used to identify and isolate ALDH(br) cells as CSCs from the 4T1 mu...

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Detalhes bibliográficos
Main Authors: Zhuang, Xiufen, Zhang, Wen, Chen, Yatong, Han, Xiangping, Li, Jie, Zhang, Yu, Zhang, Youhui, Zhang, Shuren, Liu, Binlei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541265/
https://ncbi.nlm.nih.gov/pubmed/23176143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-549
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