A Novel Oncolytic Herpes Simplex Virus Type 2 Has Potent Anti-Tumor Activity

Oncolytic viruses are promising treatments for many kinds of solid tumors. In this study, we constructed a novel oncolytic herpes simplex virus type 2: oHSV2. We investigated the cytopathic effects of oHSV2 in vitro and tested its antitumor efficacy in a 4T1 breast cancer model. We compared its effe...

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Detalhes bibliográficos
Main Authors: Zhao, Qian, Zhang, Wen, Ning, Zhifeng, Zhuang, Xiufen, Lu, Haizhen, Liang, Jing, Li, Jie, Zhang, Yu, Dong, Ying, Zhang, Youhui, Zhang, Shuren, Liu, Shangmei, Liu, Binlei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966855/
https://ncbi.nlm.nih.gov/pubmed/24671154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093103
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