c-Myc Suppression of DNA Double-strand Break Repair

c-Myc is a transcriptional factor that functions as a central regulator of cell growth, proliferation, and apoptosis. Overexpression of c-Myc also enhances DNA double-strand breaks (DSBs), genetic instability, and tumorigenesis. However, the mechanism(s) involved remains elusive. Here, we discovered...

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Bibliografiske detaljer
Main Authors: Li, Zhaozhong, Owonikoko, Taofeek K, Sun, Shi-Yong, Ramalingam, Suresh S, Doetsch, Paul W, Xiao, Zhi-Qiang, Khuri, Fadlo R, Curran, Walter J, Deng, Xingming
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540944/
https://ncbi.nlm.nih.gov/pubmed/23308051
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