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ACAT2 and ABCG5/G8 are both required for efficient cholesterol absorption in mice: evidence from thoracic lymph duct cannulation

The metabolic fate of newly absorbed cholesterol and phytosterol is orchestrated through adenosine triphosphate-binding cassette transporter G5 and G8 heterodimer (G5G8), and acyl CoA:cholesterol acyltransferase 2 (ACAT2). We hypothesized that intestinal G5G8 limits sterol absorption by reducing sub...

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Bibliografski detalji
Glavni autori: Nguyen, Tam M., Sawyer, Janet K., Kelley, Kathryn L., Davis, Matthew A., Kent, Carol R., Rudel, Lawrence L.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540850/
https://ncbi.nlm.nih.gov/pubmed/22669916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M026823
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