A dose-finding and pharmacodynamic study of bortezomib in combination with weekly paclitaxel in patients with advanced solid tumors

PURPOSE: A phase I study to determine the maximum tolerated dose (MTD) of bortezomib (B) when combined with weekly paclitaxel in patients with advanced solid tumors. PATIENTS AND METHODS: Eligible patients received escalating doses of intravenous (IV) bortezomib (0.6–2 mg/m(2)) on days 2 and 9 and I...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ramaswamy, Bhuvaneswari, Bekaii-Saab, Tanios, Schaaf, Larry J., Lesinski, Gregory B., Lucas, David M., Young, Donn C., Ruppert, Amy S., Byrd, John C., Culler, Kristy, Wilkins, Diedre, Wright, John J., Grever, Michael R., Shapiro, Charles L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540804/
https://ncbi.nlm.nih.gov/pubmed/19774377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1145-z
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