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Carotid Atherosclerotic Plaque Matrix Metalloproteinase-12–Positive Macrophage Subpopulation Predicts Adverse Outcome After Endarterectomy
BACKGROUND: Matrix metalloproteinase-12 (MMP-12) promotes atherosclerosis in animal models. MMP-12 is expressed in only a subset of foam-cell macrophages (FCMs) in human plaques. We investigated whether the prevalence of this MMP-12–expressing subpopulation is a prognostic indicator of adverse outco...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Publishing Ltd
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540663/ https://ncbi.nlm.nih.gov/pubmed/23316311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.001040 |
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