Cyclin-dependent kinase 5 is required for normal cerebellar development

Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase, and its kinase activity is dependent upon its association with either of the activating subunits p35 or p39, which are mainly expressed in neurons. We previously reported that Cdk5 knockout (KO) mice exhibit perinatal lethality, defectiv...

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Autori principali: Kumazawa, A., Mita, N., Hirasawa, M., Adachi, T., Suzuki, H., Shafeghat, N., Kulkarni, A. B., Mikoshiba, K., Inoue, T., Ohshima, T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540197/
https://ncbi.nlm.nih.gov/pubmed/23085039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.10.007
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