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Pluripotency in 3D: Genome organization in pluripotent cells

Cells face the challenge of storing two meters of DNA in the three-dimensional (3D) space of the nucleus that spans only a few microns. The nuclear organization that is required to overcome this challenge must allow for the accessibility of the gene regulatory machinery to the DNA and, in the case o...

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Bibliografiska uppgifter
Huvudupphovsmän: Denholtz, Matthew, Plath, Kathrin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540188/
https://ncbi.nlm.nih.gov/pubmed/23199754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2012.11.001
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