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Pluripotency in 3D: Genome organization in pluripotent cells
Cells face the challenge of storing two meters of DNA in the three-dimensional (3D) space of the nucleus that spans only a few microns. The nuclear organization that is required to overcome this challenge must allow for the accessibility of the gene regulatory machinery to the DNA and, in the case o...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540188/ https://ncbi.nlm.nih.gov/pubmed/23199754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2012.11.001 |
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