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Tissue-type Plasminogen Activator Protects Neurons from Excitotoxin-induced Cell Death via Activation of the ERK ½ -CREB-ATF3 Signaling Pathway
The release of the serine proteinase tissue-type plasminogen activator (tPA) from cerebral cortical neurons has a neuroprotective effect in the ischemic brain. Because excitotoxicity is a basic mechanism of ischemia-induced cell death here we investigated the effect of tPA on excitotoxin-induced neu...
Tallennettuna:
| Päätekijät: | , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540185/ https://ncbi.nlm.nih.gov/pubmed/23063501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.10.001 |
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