TUMOR NECROSIS FACTOR-LIKE WEAK INDUCER OF APOPTOSIS (TWEAK) AND FIBROBLAST GROWTH FACTOR-INDUCIBLE 14 (Fn14) MEDIATE CEREBRAL ISCHEMIA-INDUCED POLY(ADP-RIBOSE) POLYMERASE-1 ACTIVATION AND NEURONAL DEATH

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fibroblast growth factor-inducible 14 (Fn14) are expressed in neurons. Here we demonstrate that TWEAK induces a dose-dependent increase in neuronal death and that this effect is independent of TNF-α and mediated by NF-κB p...

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Detalhes bibliográficos
Main Authors: Haile, Woldeab B., Echeverry, Ramiro, Wu, Fang, Guzman, Johanna, An, Jie, Wu, Jialing, Yepes, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991428/
https://ncbi.nlm.nih.gov/pubmed/20955770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.10.029
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