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Chronic clozapine reduces rat brain arachidonic acid metabolism by reducing plasma arachidonic acid availability
Chronic administration of mood stabilizers to rats downregulates the brain arachidonic acid (AA) cascade. This downregulation may explain their efficacy against bipolar disorder (BD), in which brain AA cascade markers are elevated. The atypical antipsychotics, olanzapine (OLZ) and clozapine (CLZ), a...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540173/ https://ncbi.nlm.nih.gov/pubmed/23121637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12078 |
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