Dynamic Increase in Extracellular ATP Accelerates Photoreceptor Cell Apoptosis via Ligation of P2RX7 in Subretinal Hemorrhage

Photoreceptor degeneration is the most critical cause of visual impairment in age-related macular degeneration (AMD). In neovascular form of AMD, severe photoreceptor loss develops with subretinal hemorrhage due to choroidal neovascularization (CNV), growth of abnormal blood vessels from choroidal c...

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Detalhes bibliográficos
Main Authors: Notomi, Shoji, Hisatomi, Toshio, Murakami, Yusuke, Terasaki, Hiroto, Sonoda, Shozo, Asato, Ryo, Takeda, Atsunobu, Ikeda, Yasuhiro, Enaida, Hiroshi, Sakamoto, Taiji, Ishibashi, Tatsuro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540091/
https://ncbi.nlm.nih.gov/pubmed/23308196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053338
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