TNF-α Decreases VEGF Secretion in Highly Polarized RPE Cells but Increases It in Non-Polarized RPE Cells Related to Crosstalk between JNK and NF-κB Pathways

Asymmetrical secretion of vascular endothelial growth factor (VEGF) by retinal pigment epithelial (RPE) cells in situ is critical for maintaining the homeostasis of the retina and choroid. VEGF is also involved in the development and progression of age-related macular degeneration (AMD). We studied...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Terasaki, Hiroto, Kase, Satoru, Shirasawa, Makoto, Otsuka, Hiroki, Hisatomi, Toshio, Sonoda, Shozo, Ishida, Susumu, Ishibashi, Tatsuro, Sakamoto, Taiji
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726732/
https://ncbi.nlm.nih.gov/pubmed/23922887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069994
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker