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Perlecan Maintains Microvessel Integrity In Vivo and Modulates Their Formation In Vitro

Perlecan is a heparan sulfate proteoglycan assembled into the vascular basement membranes (BMs) during vasculogenesis. In the present study we have investigated vessel formation in mice, teratomas and embryoid bodies (EBs) in the absence of perlecan. We found that perlecan was dispensable for blood...

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Detalhes bibliográficos
Main Authors: Gustafsson, Erika, Almonte-Becerril, Maylin, Bloch, Wilhelm, Costell, Mercedes
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540034/
https://ncbi.nlm.nih.gov/pubmed/23320101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053715
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