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Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus

Human MTH1 (hMTH1) is an enzyme that hydrolyses several oxidized purine nucleoside triphosphates to their corresponding nucleoside monophosphates. Crystallographic studies have shown that the accurate mode of interaction between 8-oxoguanine and hMTH1 cannot be understood without determining the pos...

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Detalhes bibliográficos
Main Authors: Koga, Yukari, Inazato, Miyuki, Nakamura, Teruya, Hashikawa, Chie, Chirifu, Mami, Michi, Asuka, Yamashita, Taku, Toma, Sachiko, Kuniyasu, Akihiko, Ikemizu, Shinji, Nakabeppu, Yusaku, Yamagata, Yuriko
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539702/
https://ncbi.nlm.nih.gov/pubmed/23295485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112048002
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