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Preparation, crystallization and preliminary X-ray diffraction analysis of the DNA-binding domain of the Ets transcription factor in complex with target DNA

The Ets2 transcription factor is a member of the Ets transcription-factor family. Ets2 plays a role in the malignancy of cancer and in Down’s syndrome by regulating the transcription of various genes. The DNA-binding domain of Ets2 (Ets domain; ETSD), which contains residues that are highly conserve...

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Main Authors: Suwa, Yoshiaki, Nakamura, Teruya, Toma, Sachiko, Ikemizu, Shinji, Kai, Hirofumi, Yamagata, Yuriko
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374153/
https://ncbi.nlm.nih.gov/pubmed/18323600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108002662
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