Llwytho...

Validation of the Multiple Sensor Mechanism of the Keap1-Nrf2 System

The Keap1-Nrf2 system plays a critical role in cellular defense against electrophiles and reactive oxygen species. Keap1 possesses a number of cysteine residues, some of which are highly reactive and serves as sensors for these insults. Indeed, point mutation of Cys151 abrogates the response to cert...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Takaya, Kai, Suzuki, Takafumi, Motohashi, Hozumi, Onodera, Ko, Satomi, Susumu, Kensler, Thomas W, Yamamoto, Masayuki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539416/
https://ncbi.nlm.nih.gov/pubmed/22732183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.06.023
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