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Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier

The differentiation and reprogramming of cells are accompanied by drastic changes in the epigenetic profiles of cells. Waddington's classical model clearly describes how differentiating cells acquire their cell identity as the developmental potential of an individual cell population declines to...

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Hlavní autoři: Watanabe, Akira, Yamada, Yasuhiro, Yamanaka, Shinya
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539367/
https://ncbi.nlm.nih.gov/pubmed/23166402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0292
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