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Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier

The differentiation and reprogramming of cells are accompanied by drastic changes in the epigenetic profiles of cells. Waddington's classical model clearly describes how differentiating cells acquire their cell identity as the developmental potential of an individual cell population declines to...

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Autori principali: Watanabe, Akira, Yamada, Yasuhiro, Yamanaka, Shinya
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539367/
https://ncbi.nlm.nih.gov/pubmed/23166402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0292
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