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Embryo manipulation via assisted reproductive technology and epigenetic asymmetry in mammalian early development

The early stage of mammalian development from fertilization to implantation is a period when global and differential changes in the epigenetic landscape occur in paternally and maternally derived genomes, respectively. The sperm and egg DNA methylation profiles are very different from each other, an...

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Detalhes bibliográficos
Main Authors: Kohda, Takashi, Ishino, Fumitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539368/
https://ncbi.nlm.nih.gov/pubmed/23166403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0353
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