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Super-resolution characterization of TCR-dependent signaling clusters

Multi-molecular signaling complexes drive the earliest events of immune cell activation via immunoreceptors with unexplained specificity and speed. Fluorescence microscopy has shown that these complexes form microclusters at the plasma membrane of activated T cells upon engagement of their antigen r...

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Autori principali: Sherman, Eilon, Barr, Valarie, Samelson, Lawrence E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539238/
https://ncbi.nlm.nih.gov/pubmed/23278738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12010
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