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Resolving multi-molecular protein interactions by photoactivated localization microscopy

Multi-molecular protein complexes are critical to many cellular functions, including signaling, DNA transcription and enzymatic reactions. In spite of their importance, current research techniques such as biochemistry and diffraction-limited microscopy cannot resolve the heterogeneity and nanoscale...

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Detalhes bibliográficos
Main Authors: Sherman, Eilon, Barr, Valarie, Samelson, Lawrence E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608816/
https://ncbi.nlm.nih.gov/pubmed/23266704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2012.12.002
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