Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas

OBJECTIVE: Disability or death occurs more frequently in patients with hemorrhagic transformation (HT) after ischemic stroke. In rat models of stroke, sulfonylurea (SU) drugs such as glibenclamide (adopted US name, glyburide) confer protection against swelling and HT through actions on the novel SUR...

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Main Authors: Kunte, Hagen, Busch, Markus A., Trostdorf, Katrin, Vollnberg, Bernd, Harms, Lutz, Mehta, Rupal, Castellani, Rudolf J., Mandava, Pitchaiah, Kent, Thomas A., Simard, J. Marc
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539226/
https://ncbi.nlm.nih.gov/pubmed/23280795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23680
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