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The structural basis of direct glucocorticoid-mediated transrepression
A newly discovered negative glucocorticoid response element (nGRE) mediates DNA-dependent transrepression by the glucocorticoid receptor (GR) across the genome and plays a major role in immunosuppressive therapy. The nGRE differs dramatically from activating response elements and the mechanism drivi...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539207/ https://ncbi.nlm.nih.gov/pubmed/23222642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2456 |
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