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ATP release and purinergic signaling in NLRP3 inflammasome activation
The NLRP3 inflammasome is a protein complex involved in IL-1β and IL-18 processing that senses pathogen- and danger-associated molecular patterns (PAMPs and DAMPs). One step- or two step-models have been proposed to explain the tight regulation of IL-1β production during inflammation. Moreover, cell...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539150/ https://ncbi.nlm.nih.gov/pubmed/23316199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00414 |
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