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Nitric oxide synthases activation and inhibition by metallacarborane cluster-based isoform-specific affectors
A small library of boron cluster and metallacarborane cluster-based ligands was designed, prepared and tested for isoform-selective activation or inhibition of the three nitric oxide synthase isoforms. Based on the concept of creating a hydrophobic analog of a natural substrate, a stable and non-tox...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538847/ https://ncbi.nlm.nih.gov/pubmed/23075390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300805x |
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