RING Finger Protein 11 Targets TBK1/IKKi Kinases to Inhibit Antiviral Signaling

A key feature of the innate antiviral immune response is a rapid nonspecific response to virus infection largely mediated by the induction and extracellular secretion of type I interferons (IFNs) that restrict virus replication. Cytoplasmic sensors such as RIG-I recognize viral RNA and trigger antiv...

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Bibliographic Details
Main Authors: Charoenthongtrakul, Soratree, Gao, Linlin, Parvatiyar, Kislay, Lee, David, Harhaj, Edward W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538746/
https://ncbi.nlm.nih.gov/pubmed/23308279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053717
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