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Endotoxin- and ATP-neutralizing activity of alkaline phosphatase as a strategy to limit neuroinflammation
BACKGROUND: Alkaline phosphatase (AP) is a ubiquitously expressed enzyme which can neutralize endotoxin as well as adenosine triphosphate (ATP), an endogenous danger signal released during brain injury. In this study we assessed a potential therapeutic role for AP in inhibiting neuroinflammation usi...
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| Main Authors: | , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
BioMed Central
2012
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538711/ https://ncbi.nlm.nih.gov/pubmed/23231745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-266 |
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