Bovine Intestinal Alkaline Phosphatase Attenuates the Inflammatory Response in Secondary Peritonitis in Mice

Lipopolysaccharide (LPS) contributes importantly to morbidity and mortality in sepsis. Bovine intestinal alkaline phosphatase (BIAP) was demonstrated to detoxify LPS through dephosphorylation. LPS injection combined with BIAP reduced inflammation and improved survival in various experimental setting...

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Detalhes bibliográficos
Main Authors: van Veen, Suzanne Q., van Vliet, Arlène K., Wulferink, Marty, Brands, Ruud, Boermeester, Marja A., van Gulik, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168548/
https://ncbi.nlm.nih.gov/pubmed/15972524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.7.4309-4314.2005
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