Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines

The use of DNA and viral vector-based vaccines for the induction of cellular immune responses is increasingly gaining interest. However, concerns have been raised regarding the safety of these immunization strategies. Due to the lack of their genome integration, mRNA-based vaccines have emerged as a...

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Bibliografski detalji
Glavni autori: Pollard, Charlotte, Rejman, Joanna, De Haes, Winni, Verrier, Bernard, Van Gulck, Ellen, Naessens, Thomas, De Smedt, Stefaan, Bogaert, Pieter, Grooten, Johan, Vanham, Guido, De Koker, Stefaan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538310/
https://ncbi.nlm.nih.gov/pubmed/23011030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.202
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