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Absence of Oncogenic Canonical Pathway Mutations in Aggressive Pediatric Rhabdoid Tumors

BACKGROUND: Rhabdoid tumors (also called atypical teratoid/rhabdoid tumor (AT/RT) in the brain), are highly malignant, poor prognosis lesions arising in the kidneys, soft tissues and central nervous system. Targeted therapy in this disease would benefit from advanced technologies detecting relevant...

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Detalhes bibliográficos
Main Authors: Kieran, Mark W., Roberts, Charles W.M., Chi, Susan N., Ligon, Keith L., Rich, Benjamin E., MacConaill, Laura E., Garraway, Levi A., Biegel, Jaclyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538080/
https://ncbi.nlm.nih.gov/pubmed/22997201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24315
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