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High Throughput Genotyping in Osteosarcoma Identifies Multiple Mutations in PIK3CA and other Oncogenes

BACKGROUND: Identification of new genes that are mutated in osteosarcomas is critical to developing a better understanding of the molecular pathogenesis of this disease and discovering new targets for therapeutic development. METHODS: We identified somatic non-synonymous coding mutations in oncogene...

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Detalhes bibliográficos
Main Authors: Choy, Edwin, Hornicek, Francis, MacConaill, Laura, Harmon, David, Tariq, Zeeshan, Garraway, Levi, Duan, Zhenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272156/
https://ncbi.nlm.nih.gov/pubmed/22006429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26617
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