Targeted Delivery of Paclitaxel to EphA2-Expressing Cancer Cells

PURPOSE: YSA is an EphA2-targeting peptide that effectively delivers anti-cancer agents to prostate cancer tumors (1). Here, we report on how we increased the drug-like properties of this delivery system. EXPERIMENTAL DESIGN: By introducing non-natural amino acids, we have designed two new EphA2 tar...

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Detalhes bibliográficos
Main Authors: Wang, Si, Noberini, Roberta, Stebbins, John L., Das, Swadesh, Zhang, Ziming, Wu, Bainan, Mitra, Sayantan, Billet, Sandrine, Fernandez, Ana, Bhowmick, Neil A., Kitada, Shinichi, Pasquale, Elena B., Fisher, Paul B., Pellecchia, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537892/
https://ncbi.nlm.nih.gov/pubmed/23155185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2654
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