SSEA-5, an antibody defining a novel surface glycan on human pluripotent stem cells and its application to remove teratoma-forming cells as part of a surface antibody panel

A significant risk in the clinical application of human pluripotent stem cells (hPSCs), including human embryonic and induced pluripotent stem cells (hESCs and hiPSCs), is teratoma formation from residual undifferentiated cells. We have raised a monoclonal antibody (mAb) against hESCs, designated SS...

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Main Authors: Tang, Chad, Lee, Andrew S., Volkmer, Jens-Peter, Sahoo, Debashis, Nag, Divya, Mosley, Adriane R., Inlay, Matthew A., Ardehali, Reza, Chavez, Shawn L., Pera, Renee Reijo, Behr, Barry, Wu, Joseph C., Weissman, Irving L., Drukker, Micha
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537836/
https://ncbi.nlm.nih.gov/pubmed/21841799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1947
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