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Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors
The promise of pluripotent stem cells as a research and therapeutic tool is partly undermined by the technical challenges of generating and maintaining these cells in culture. Human embryonic stem cells (hESCs) are exquisitely sensitive to culture conditions, and require constant signaling by growth...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044421/ https://ncbi.nlm.nih.gov/pubmed/21300885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019047108 |
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