Assessment of the Role of the Central DNA Flap in Human Immunodeficiency Virus Type 1 Replication by Using a Single-Cycle Replication System

In this study, reverse transcriptase (RT)- and integrase (IN)-defective human immunodeficiency virus type 1 (HIV-1) was transcomplemented with Vpr-RT-IN fusion proteins to delineate pol sequences important for HIV-1 replication. Our results reveal that a 194-bp sequence encompassing the 3′end of the...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Ao, Zhujun, Yao, Xiaojian, Cohen, Éric A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Assuntos:
Replication
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14990738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.6.3170-3177.2004
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