Assessment of the Role of the Central DNA Flap in Human Immunodeficiency Virus Type 1 Replication by Using a Single-Cycle Replication System

In this study, reverse transcriptase (RT)- and integrase (IN)-defective human immunodeficiency virus type 1 (HIV-1) was transcomplemented with Vpr-RT-IN fusion proteins to delineate pol sequences important for HIV-1 replication. Our results reveal that a 194-bp sequence encompassing the 3′end of the...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Ao, Zhujun, Yao, Xiaojian, Cohen, Éric A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Replication
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14990738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.6.3170-3177.2004
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