Interactions Required for Binding of Simian Virus 40 T Antigen to the Viral Origin and Molecular Modeling of Initial Assembly Events

The purified T-antigen origin binding domain binds site specifically to site II, the central region of the simian virus 40 core origin. However, in the context of full-length T antigen, the origin binding domain interacts poorly with DNA molecules containing just site II. Here we investigate the con...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Reese, Danielle K., Sreekumar, Kodangattil R., Bullock, Peter A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Replication
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353773/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14990710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.6.2921-2934.2004
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