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Interactions Required for Binding of Simian Virus 40 T Antigen to the Viral Origin and Molecular Modeling of Initial Assembly Events

The purified T-antigen origin binding domain binds site specifically to site II, the central region of the simian virus 40 core origin. However, in the context of full-length T antigen, the origin binding domain interacts poorly with DNA molecules containing just site II. Here we investigate the con...

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Detalles Bibliográficos
Main Authors: Reese, Danielle K., Sreekumar, Kodangattil R., Bullock, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC353773/
https://ncbi.nlm.nih.gov/pubmed/14990710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.2921-2934.2004
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