Treatment with Anti-LFA-1 Delays the CD8(+) Cytotoxic-T-Lymphocyte Response and Viral Clearance in Mice with Primary Respiratory Syncytial Virus Infection

Cytotoxic T lymphocytes (CTLs) play an important role in the immune response against respiratory syncytial virus (RSV) infection. The cell surface molecule lymphocyte function-associated antigen 1 (LFA-1) is an important contributor to CTL activation, CTL-mediated direct cell lysis, and lymphocyte m...

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Udgivet i:J Virol
Main Authors: Rutigliano, John A., Johnson, Teresa R., Hollinger, Tonya N., Fischer, Julie E., Aung, Sandra, Graham, Barney S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353752/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14990720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.6.3014-3023.2004
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