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Proteasomes, TAP and ERAAP control CD4(+) T(H) cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens()
Cytoplasmic Ags derived from viruses, cytosolic bacteria, tumours and allografts are presented to T cells by MHC class I or class II molecules. In the case of class II-restricted Ags, professional Ag-presenting cells acquire them during uptake of dead, class II-negative cells and present them via a...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537507/ https://ncbi.nlm.nih.gov/pubmed/21572029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100525 |
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