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Proteasomes, TAP and ERAAP control CD4(+) T(H) cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens()

Cytoplasmic Ags derived from viruses, cytosolic bacteria, tumours and allografts are presented to T cells by MHC class I or class II molecules. In the case of class II-restricted Ags, professional Ag-presenting cells acquire them during uptake of dead, class II-negative cells and present them via a...

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Bibliografiske detaljer
Main Authors: Dragovic, Srdjan M., Hill, Timothy, Christianson, Gregory J., Kim, Sungjune, Elliott, Tim, Scott, Diane, Roopenian, Derry C., Van Kaer, Luc, Joyce, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537507/
https://ncbi.nlm.nih.gov/pubmed/21572029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100525
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