IL-10 produced by iTreg cells controls colitis and pathogenic ex-iTreg cells during immunotherapy

“Natural” regulatory T (nTreg) cells that express the transcription factor Foxp3 and produce IL-10 are required for systemic immunological tolerance. “Induced” Treg (iTreg) cells are non-redundant and essential for tolerance at mucosal surfaces, yet their mechanisms of suppression and stability are...

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Bibliografiske detaljer
Main Authors: Schmitt, Erica G., Haribhai, Dipica, Williams, Jason B., Aggarwal, Praful, Jia, Shuang, Charbonnier, Louis-Marie, Yan, Ke, Lorier, Rachel, Turner, Amy, Ziegelbauer, Jennifer, Georgiev, Peter, Simpson, Pippa, Salzman, Nita H., Hessner, Martin J., Broeckel, Ulrich, Chatila, Talal A., Williams, Calvin B.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537488/
https://ncbi.nlm.nih.gov/pubmed/23125413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200936
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