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IL-10 produced by iTreg cells controls colitis and pathogenic ex-iTreg cells during immunotherapy
“Natural” regulatory T (nTreg) cells that express the transcription factor Foxp3 and produce IL-10 are required for systemic immunological tolerance. “Induced” Treg (iTreg) cells are non-redundant and essential for tolerance at mucosal surfaces, yet their mechanisms of suppression and stability are...
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| 主要な著者: | , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537488/ https://ncbi.nlm.nih.gov/pubmed/23125413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200936 |
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