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The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans
Aberrations in the p53 tumor suppressor pathway are associated with hematologic malignancies. p53-dependent cell cycle control, senescence, and apoptosis functions are actively involved in maintaining hematopoietic homeostasis under normal and stress conditions. Whereas loss of p53 function promotes...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Hematology
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537308/ https://ncbi.nlm.nih.gov/pubmed/23018641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-356014 |
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