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Human Cytomegalovirus Stimulates Cellular IKK2 Activity and Requires the Enzyme for Productive Replication
Human cytomegalovirus (HCMV) exploits the host transcription factor NF-κB to enhance its own replication, dissemination, and reactivation from latency. Here we report that HCMV infection activates the upstream IκB kinase (IKK) complex and that its catalytic IKK2 subunit is required for HCMV-induced...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC353729/ https://ncbi.nlm.nih.gov/pubmed/14990741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.3190-3195.2004 |
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