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Human Cytomegalovirus Stimulates Cellular IKK2 Activity and Requires the Enzyme for Productive Replication

Human cytomegalovirus (HCMV) exploits the host transcription factor NF-κB to enhance its own replication, dissemination, and reactivation from latency. Here we report that HCMV infection activates the upstream IκB kinase (IKK) complex and that its catalytic IKK2 subunit is required for HCMV-induced...

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Bibliografiske detaljer
Main Authors: Caposio, Patrizia, Dreano, Michel, Garotta, Gianni, Gribaudo, Giorgio, Landolfo, Santo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC353729/
https://ncbi.nlm.nih.gov/pubmed/14990741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.3190-3195.2004
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