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Human Cytomegalovirus Stimulates Cellular IKK2 Activity and Requires the Enzyme for Productive Replication

Human cytomegalovirus (HCMV) exploits the host transcription factor NF-κB to enhance its own replication, dissemination, and reactivation from latency. Here we report that HCMV infection activates the upstream IκB kinase (IKK) complex and that its catalytic IKK2 subunit is required for HCMV-induced...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Caposio, Patrizia, Dreano, Michel, Garotta, Gianni, Gribaudo, Giorgio, Landolfo, Santo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC353729/
https://ncbi.nlm.nih.gov/pubmed/14990741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.3190-3195.2004
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